Markos Kounalakis Markos Kounalakis

As Washington Falters, California Leads the Way on Scientific Research

The government and its people are bound by a compact: Citizens finance their government, delegate it life-and-death powers, and expect security. This is not just a military or police matter; it also concerns protecting public health through vaccines, food inspection, and cutting-edge scientific research. In recent decades, however, Washington has frequently abdicated this core responsibility, paralyzed by ideology or incompetence, leaving a vacuum. Invariably, California steps in to fill it. 

This is not a story of partisanship or the most populous state using its clout. It is pragmatic self-preservation and strategic foresight. When Washington falters, California—leveraging its economic might, its world-class institutions, and its people—acts as a de facto nation-state to safeguard its future and the rest of the nation’s, whether through auto emissions or food safety. This trend reveals a critical shift in the American federalist system, where a single state has become an essential backstop for national progress. At the time of the Republic’s founding, the population difference between the most and least populous states was 10 to 1. Now it’s over 70-to-1.   READ MORE

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Markos Kounalakis Markos Kounalakis

Quest for the Fountain of Youth remains a continually updated story

Ponce de Leon sought it in Florida. Alexander the Great expanded his empire to find it in the East. Now, in the latest search for eternal youth, an American company hopes to make you vibrant and spry by having youthful blood coursing through your system.

Globally, all countries and people share this one desire for a healthier and slower aging process, but if past results are any indication of future prospects, the next elixir, cell therapy, or blood transfusion may be a futile and, perhaps, dangerous search for a panacea.

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Ambrosia Medical is the latest entrant in the all-too-human race for immortality or, at least, healthy longevity. For $8,000-$12,000, the company says that it can deliver nutrient-rich, youthful blood to the aged, the hopeful and, maybe, the hypochondriac crowd. In vague terms and using limited research, the company intimates a promise of parabiosis — a rejuvenated vigor and refreshed immunity to both illness and aging. READ MORE

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